Laboratory of Pharmacy Practice and Science Ⅳ

原著論文

2024
Wataru Ando, Masaya Sogabe, Shigemi Ishikawa, Takayuki Uematsu, Hiroyuki Furuya, Hiroaki Yokomori, Yutaka Kohgo, Katsuya Otori, Tomoyuki Nakano, Shunsuke Endo, Hiroyuki Tsubochi, Isao Okazaki
Matrix metalloproteinase?1 and microRNA?486?5p in urinary exosomes can be used to detect early lung cancer: A preliminary report.
Oncology letters 27(3) 127


2023
Hidetoshi Ishii, Risa Sawada, Megumi Shiomi, Kiyoshi Shibuya
A case-control study showing low creatinine clearance and high magnesium intake as risk factors for hypermagnesemia in older individuals
Magnesium research 36(2) 23-30

Mitsuki Jimbo, Sakae Saito, Takayuki Uematsu, Hideaki Hanaki, Katsuya Otori, Kiyoshi Shibuya, Wataru Ando
Risk analysis of COVID-19 hospitalization and critical care by race and region in the United States: a cohort study 
BMC Public Health 23(1) 1489

2022
吉田 和佳奈, 齋藤 栄, 酒向 孫市, 野田 政充, 川口 諭, 新井 一也, 安齋 沙織, 久保田 聡, 渋谷 清, 町田 充, 堀野 忠夫, 青木 学一, 尾鳥 勝也
円盤型散薬分包機に付着したメルカプトプリンの水拭きによる除去を行った薬局の2例 
YAKUGAKU ZASSHI 142(8) 893-900 

Wataru Ando, Takeshi Horii, Mitsuki Jimbo, Takayuki Uematsu, Koichiro Atsuda, Hideaki Hanaki, Katsuya Otori.
Smoking cessation in the elderly as a sign of susceptibility to symptomatic COVID-19 reinfection in the United States. 
Frontiers in public health 10 985494-985494

Wataru Ando, Fumihiko Kaneko, Satoshi Shimamoto, Koji Igarashi, Katsuya Otori, Hiroaki Yokomori
Long-term prediction of hepatocellular carcinoma using serum autotaxin levels after antiviral therapy for hepatitis C. 
Annals of hepatology 27(2) 100660

2021
Megumi Shiomi, Momoka Kurobuchi, Yoichi Tanaka, Tesshu Takada, Katsuya Otori.
Pill Counting in the Determination of Factors Affecting Medication Adherence in Patients with Type 2 Diabetes: A Retrospective Observational Study. 
Diabetes therapy: research, treatment and education of diabetes and related disorders 12(7) 1993-2005

Wataru Ando, Takeshi Horii, Takayuki Uematsu, Hideaki Hanaki, Koichiro Atsuda, Katsuya Otori.
Impact of overlapping risks of type 2 diabetes and obesity on coronavirus disease severity in the United States. 
Scientific reports 11(1) 17968-17968

Hiroaki Yokomori, Wataru Ando, Masaya Oda. 
Plasmalemmal Vesicle-Associated Protein Is Associated with Endothelial Cells Sprouting from the Peribiliary Capillary Plexus in Human Cirrhotic Liver. 
Journal of vascular research 19:1-9

Manahito Aoki, Midori Naya, Shiho Arima, Kaori Shinohara, Masahiro Kato, Kiyoshi Shibuya, Masaki Ohtawa, Tohru Nagamitsu, Katsuya Otori.
Mixture of clopidogrel bisulfate and magnesium oxide tablets reduces clopidogrel dose administered through a feeding tube 
Journal of Pharmaceutical Health Care and Sciences 7(1)

塩見めぐみ, 田中庸一, 尾鳥勝也.
薬学実務実習ガイドラインを基に考案した病院実習プログラムの評価.
薬学教育 5 2021年9月

婦川貴博, 冨澤淳, 椎崇, 佐々木善信, 新井万理子, 吉田尚美, 松原肇, 横田訓男, 尾鳥勝也, 厚田幸一郎.
病院薬剤師のトレーシングレポート活用に関する意識調査～トレーシングレポートの活用推進に向けて～. 
日本薬剤師会雑誌 73(8) 837-841 2021年8月

2020
菅野雄太, 向井潤一, 鎌田裕介, 菅原大輔, 久保田理恵, 尾鳥勝也, 高岩徹幸.
感染症に伴う播種性血管内凝固症候群に対する遺伝子組換えトロンボモデュリンアルファ製剤の投与日数に関する後方視的検討. 
医療薬学 47(1) 43-53 2021年1月

Isao Okazaki, Shinsuke Shibata, Wataru Ando, Takayo Yanagawa, Hiroaki Yokomori, Akira Sonoda, Norihiko Suzuki, Eigoro Yamanouchi, Shinya Okada, Shinichi Kamikura, Kazuaki Hachimura, Takashi Takaki, Katsuya Otori, Yutaka Suzuki, Hideyuki Okano, Yutaka Inagaki.
Sequential Matrix Metalloproteinase-1 Expression Triggered by Infiltrating Monocytic Lineage Cells Modulates Pathophysiological Aspects of Human Nonalcoholic Steatohepatitis. 
Metalloproteinases In Medicine 7(1) 1-13

Hiroaki Yokomori, Wataru Ando.
Spatial expression of glucagon-like peptide 1 receptor and caveolin-1 in hepatocytes with macrovesicular steatosis in non-alcoholic steatohepatitis. 
BMJ open gastroenterology 7(1)

Manahito Aoki, Satsuki Oda, Satoshi Kubota, Sakae Saito, Norio Yokota, Atsushi Shibazaki, Kiyoshi Shibuya, Magoichi Sako, Katsuya Otori.
Safe Handling Method for Splitting Azathioprine Tablets. 
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 141(1) 125-133

Megumi Shiomi, Yoichi Tanaka, Tesshu Takada, Katsuya Otori.
Determining whether the effect of liraglutide on non‐alcoholic fatty liver disease depends on reductions in the body mass index. 
JGH open 34(4) 995-1001

2019
Wataru Ando, Yumika Imamura, Hideyuki Nagashima, Kouji Kondo, Kazunori Nakamura, Katsuya Otori. 
Handling and packaging of medical bags at acute disaster sites under high-temperature conditions. 
BMC research notes 13(1) 158-158

Ando W, Kikuchi K, Uematsu T, Yokomori H, Takaki T, Sogabe M, Kohgo Y, Otori K, Ishikawa S, Okazaki I. Novel breast cancer screening: combined expression of miR-21 and MMP-1 in urinary exosomes detects 95% of breast cancer without metastasis. Sci Rep. 2019 Sep 19;9(1):13595

Tanaka Y, Inoue A, Mizunuma T, Matsumura H, Yokomori H, Komiyama T, Otori K. Tolerability of erythrocyte ribavirin triphosphate concentrations depends on the ITPA genotype. Ther Drug Monit 2019 Aug; 41/ 4, 497-502.

Aoki M, Hamasaki Y, Naya M, Shishikura H, Kato M, Shibuya K, Aoyagi M, Otori K. Evaluation of Measures against Exposure during Administration of Hazardous Drugs through a Feeding Tube. Biol. Pharm. Bull.2019 Nov;42(11), 1823-1829.


2018

Shiomi M, Takada T, Tanaka Y, Yajima K, Isomoto A, Sakamoto M, Otori K.
Clinical factors associated with the occurrence of nausea and vomiting in type 2 diabetic patients treated with glucagon-like peptide-1 receptor agonists. J Diabetes Investig 2019 Mar;10(2), 408-417

青木学一，久保田聡，今野友貴，大和田真未，小田さつき，横田訓男，柴﨑　淳，渋谷　清，尾鳥勝也. メトトレキサート錠およびシクロホスファミド錠の粉砕調剤における分包機の汚染除去に効果的な清掃法の検討. 日本病院薬剤師会雑誌 2019 Mar;55(3), 273-278.

Yokomori H, Ando W, Oda M. Cavin-1 is linked to lipid droplet formation in human hepatic stellate cells. Med Mol Morphol. 2019 Mar 15. doi: 10.1007/s00795-019-00219-4. [Epub ahead of print]

Yokomori H, Ando W, Oda M.
Caveolin-1 is related to lipid droplet formation in hepatic stellate cells in human liver. 
Acta Histochemica 2019 Feb; 121:113-118.

Yang JJ, Whirl‐Carrillo M, Scott SA, Turner AJ, Schwab M, Tanaka Y, Suarez‐Kurtz G, Schaeffeler E, Klein TE, Miller NA, Gaedigk A.
Pharmacogene Variation Consortium Gene Introduction: NUDT15.
Clin Pharmacol Ther. 2018 [Epub ahead of print]

Yokomori H, Ando W, Kaneko K, Suzuki H, Igarashi K, Oda M.
Autotaxin and vascular endothelial growth factor receptor-2 and -3 relate vascular development in chronic viral hepatitis C progression.
APMIS 2018 Nov; 126:913-921

Kondo Y, Fukuyama T, Yamamura R, Futawatari N, Ichiki Y, Tanaka Y, Nishi Y, Takahashi Y, Yamazaki H, Kobayashi N, Watanabe M.
Detection of KK-LC-1 Protein, a Cancer/Testis Antigen, in Patients with Breast Cancer.
Anticancer Research. 2018 Oct; 38(10):5923-5928

Tanaka Y, Yokomori H, Otori K
Induction of inosine triphosphatase activity during ribavirin treatment for chronic hepatitis C.
Clin Chim Acta 2018 Jul; 482:16-20

Ando W, Yokomori H, Kaneko F, Kaneko M, Igarashi K, Suzuki H.
Serum Autotaxin Concentrations Reflect Changes in Liver Stiffness and Fibrosis following Antiviral Therapy in a Patient with Chronic Hepatitis C.
Hepatology Communications 2018 Sep; 2(9):1111-1122

Shiomi M, Takada T, Tanaka Y, Yajima K, Isomoto A, Sakamoto M, Otori K.
Clinical factors associated with the occurrence of nausea and vomiting in type 2 diabetic patients treated with glucagon-like peptide-1 receptor agonists.
J Diabetes Investig. 2018 Jul 23. [Epub ahead of print]

Kubota R, Shibuya K, Tanaka Y, Aoki M, Shiomi M, Ando W, Otori K, Komiyama T.
Clinical Pharmacy Education in Japan: Using Simulated Patients in Laboratory-Based Communication-Skills Training before Clinical Practice. Pharmacy (Basel). 2018 Jun 1;6(2). pii: E49

Tanaka Y, Yokomori H, Otori K
Induction of inosine triphosphatase activity during ribavirin treatment for chronic hepatitis C
Clin Chim Acta. 2018 Jul;482:16-20

Ando W, Yokomori H, Tsutsui N, Yamanouchi E, Suzuki Y, Oda M, Inagaki Y, Otori K, Okazaki I.
Serum Matrix Metalloproteinase-1 Level Represents Disease Activity as Opposed to Fibrosis in Patients with Histologically Proven Nonalcoholic Steatohepatitis. Clin Mol Hepato. 2018 Mar;24(1):61-76

Huang M, Inukai T, Miyake K, Tanaka Y, Kagami K, Abe M, Goto H, Minegishi M, Iwamoto S, Sugihara E, Watanabe A, Somazu S, Shinohara T, Oshiro H, Akahane K, Goi K, Sugita K.
Clofarabine exerts antileukemic activity against cytarabine-resistant B-cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression. Cancer Med. 2018 Apr;7(4):1297-1316

Urayama KY, Takagi M, Kawaguchi T, Matsuo K, Tanaka Y, Ayukawa Y, Arakawa Y, Hasegawa D, Yuza Y, Kaneko T, Noguchi Y, Taneyama Y, Ota S, Inukai T, Yanagimachi M, Keino D, Koike K, Toyama D, Nakazawa Y, Kurosawa H, Nakamura K, Moriwaki K, Goto H, Sekinaka Y, Morita D, Kato M, Takita J, Tanaka T, Inazawa J, Koh K, Ishida Y, Ohara A, Mizutani S, Matsuda F, Manabe A. 
Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese.
Sci Rep. 2018; 8/ 1, 789


2017

Tokumoto M,Shibuya K, Jin-Yong Lee, Tohyama C, Satoh M,
Effect of metallothionein on ethanol-induced hepatotoxicity in mice.
Fundam Toxicol Sci  . 2017;4(6):269-273

田中　庸一. 
日本人小児急性リンパ性白血病におけるNUDT15とABCC4遺伝子多型の6-メルカプトプリン感受性への影響. 
臨床血液. 2017;58(8):950-956

Ando W, Yokomori H, Otori K, Oda M.
The Apelin Receptor APJ in Hematopoietic Stem Cells/Progenitor Cells in the Early Stage of Non-Alcoholic Steatohepatitis.
J Clin Med Res. 2017;9(9):809-811

Yokomori H, Oda M, Ando W, Inagaki Y, Okazaki I.
Hepatic progenitor cell expansion in early-stage nonalcoholic steatohepatitis: evidence from immunohistochemistry and immunoelectron microscopy of matrix metalloproteinase-1.
Med Mol Morphol. 2017/06

Tanaka Y, Nakadate H, Kondoh K, Koh K, Manabe A.
Interaction between NUDT15 and ABCC4 variants enhances intolerability of 6-mercaptopurine in Japanese patients with childhood acute lymphoblastic leukemia. 
Pharmacogenomics Journal. 2017/04

塩見めぐみ, 田中庸一, 坂本将規, 磯元晃, 中村麻美, 高田哲秀, 小宮山貴子. 
リラグルチドの治療効果評価時期および血糖改善効果の予測因子に関する検討. 
糖尿病. 2017; 60(5):361-369.

久保田理恵，石川亜里沙，尾鳥勝也.
二次救急病院の救急センターにおける医薬品の使用実態と適正使用に向けての評価.　
薬事新報. 2017;2986:333-337

Ando W, Yokomori H, Isomoto A, Tachibana H, Tsutsui N, Inagaki Y, Isao Okazaki, Komiyama T.
Serum apelin-36 level is useful for early detection of liver fibrosis in nonalcoholic steatohepatitis patients.
Kitasato Med J. 2017;47(2):129-140

Ando W, Fukunaga, Y, Yokomori H, Komiyama T.
Reduced telaprevir dosing in combination therapy for patients with chronic hepatitis C.
Kitasato Med J. 2017;47(1):1-9

2016

青木学一
第5回　簡易懸濁法研究会　実技セミナー in 東京に参加して
簡易懸濁法研究会会誌. 2016;4(2): 21

青木学一，戸根奈津子，金澤温子，満木由布菜，吉田涼平，渋谷 清，久保田理恵，酒向孫市，小宮山貴子
飛散したロイケリン^®散10%の環境曝露に配慮した清掃処理法－調剤現場での実施例－
日本病院薬剤師会雑誌. 2016;52(3):287-291.

田中庸一 
アジア人に特徴的なチオプリン感受性要因：NUDT15多型. 
ファルマシア. 2016; 52(12):1161.

田中庸一
白血病治療におけるpharmacogenomics.
臨床血液. 2016; 57(7):910-918.

深尾大輔，濱畑啓悟，高橋俊恵，古宮　圭，井上美保子，原　茂登，儘田光和，吉田　晃，百井　亨，田中庸一.
T細胞性急性リンパ性白血病に対する維持療法中に6-メルカプトプリンによる著明な骨髄抑制をきたしNUDT15 変異を認めた1 例. 
日本小児血液?がん学会雑誌. 2016; 53(2):139-142.

木村俊介，長谷川大輔，吉本優里，平林真介，細谷要介，吉原宏樹，熊本忠史，田中庸一，真部　淳
メルカプトプリンによる重度の血液毒性をきたしたNUDT15ホモバリアントを有する小児急性リンパ性白血病. 
臨床血液. 2016; 57(6):748-753.

Tanaka Y, Tamura Y, Yokomori H, Komiyama T.
Rapidity and Severity of Hemoglobin Decreasing Associated with Erythrocyte Inosine Triphosphatase Activity and ATP Concentration during Chronic Hepatitis C Treatment. 
BIOL PHARM BULL. 2016; 39(4):615-619.

Okazaki I, Ishikawa S, Ando W, Sohara Y.
Lung adenocarcinoma in never smokers: Problems of primary prevention from aspects of susceptible genes and carcinogens. 
Anticancer Research. 2016; 36(12):6207-6224.

Yokomori H, Inagaki Y, Ando W, Hara M, Komiyama T, Kojima S, Oda M, Kuroda H, Suzuki Y, Okazaki I.
Spatiotemporal expression of matrix metalloproteinase-1 in progression of nonalcoholic steatohepatitis. 
Journal of Modern Human Pathology. 2016; 1(2):11–20.

2015
歌野智之，田中庸一，木津純子，神谷尚宏，小川千登世，石田也寸志，細谷亮太，真部　淳. 
小児急性リンパ性白血病の維持療法期間におけるメルカプトプリン 及びメトトレキサート投与量の推移～単施設における検討～. 
小児血液?がん学会雑誌. 2015; 52(5): 399-404.

田中庸一
Introduce My Article. 臨床血液. 2015; 56(11): 2358.

塩見めぐみ
GLP-1 受容体作動薬の使い分けについて. 
CDEJ News Letter. 2015; 48:12

Tanaka Y, Kato M, Hasegawa D, Urayama KY, Nakadate H, Kondoh K, Nakamura K, Koh K, Komiyama T, Manabe A.
Susceptibility to 6-MP toxicity conferred by a NUDT15 variant in Japanese children with acute lymphoblastic leukaemia. 
British journal of haematology. 2015; 171(1):109-115.

Tanaka Y, Manabe A, Fukushima H, Suzuki R, Nakadate H, Kondoh K, Nakamura K, Koh K, Fukushima T, Tsuchida M, Koike K, Kiyokawa N, Noguchi E, Sumazaki R, Komiyama T.
Multidrug resistance protein 4 (MRP4) polymorphisms impact the 6-mercaptopurine dose tolerance during maintenance therapy in Japanese childhood acute lymphoblastic leukemia. 
Pharmacogenomics Journal. 2015; 15(4):380-384.

田中庸一. Introduce My Article. 臨床血液. 2015; 56(1): 51.

Yokomori H, Ando W, Yoshimura K, Yamazaki H, Takahashi Y, Oda M.
Increases in endothelial caveolin-1 and cavins correlate with cirrhosis progression.
Micron. 2015; 76:52-61. 

2014
尾鳥勝也，猪腰淳嗣，矢後和夫，供田洋
静注用人免疫グロブリン製剤の品質比較試験. 
医療薬学. 2014;40(8):433-440.

Tanaka Y, Manabe A, Nakadate H, Kondoh K, Nakamura K, Koh K, Kikuchi A, Komiyama T.
Methylenetetrahydrofolate reductase gene haplotypes affect toxicity during maintenance therapy for childhood acute lymphoblastic leukemia in Japanese patients.
Leukemia and Lymphoma. 2014; 55(5):1126-1131.

Iguchi H, Oda M, Yamazaki H, Yoshimura K, Ando W, Yokomori H.
Aquaporin-1 is associated with arterial capillary proliferation and hepatic sinusoidal transformation contributing to portal hypertension in primary biliary cirrhosis. 
Med Mol Morphol. 2014; 47(2):90-9.

2013
Kubota R, Komiyama T, Miwa Y, Bun S, Ishii J, Minei S, Irie A.
Pharmacokinetics of Ketamine and Norketamine After Oral Administration of a Liquid Formulation of Ketamine.
J Curr Surg. 2013;3(2):82-86

2012
Tanaka Y, Manabe A, Nakadate H, Kondoh K, Nakamura K, Koh K, Utano T, Kikuchi A, Komiyama T.
The activity of the inosine triphosphate pyrophosphatase affects toxicity of 6-mercaptopurine during maintenance therapy for acute lymphoblastic leukemia in Japanese children. 
Leukemia Research. 2012; 36(5):560-564.