Analytical Unit for Organic Chemistry

2023

2022

Ishida, K.; Tanaka, T.; Nagai, K.; Furuichi, Y.; Terahara, T.; Ando, M. Tsukamasa, Y.; Fukuda, T. New dihydronaphthothiophene derivatives by the biological transformation of seriniquinone using marine-derived actinomycete Streptomyces albogriseolus OM27-12. J. Antibiot. 2022, 75, 548-533 .

Uraguchi, S.; Ohshiro, Y.; Otsuka, Y.; Wada, E.; Naruse, F.; Sugaya, K.; Nagai, K.; Wongkaew, A.; Nakamura, R.; Takanezawa, Y.; Clemens, S.; Ohkama-Ohtsu, N.; Kiyono, M. Phytochelatin‐mediated metal detoxification pathway is crucial for an organomercurial phenylmercury tolerance in Arabidopsis. Plant Molecular Biology 2022, 109, 563-577.

2021

Uraguchi, S.; Nagai, K.; Naruse, F.; Otsuka, Y.; Ohshiro, Y.; Nakamura, R.; Takanezawa, Y.; Kiyono, M. Development of affinity beads-based in vitro metal-ligand binding assay reveals dominant cadmium affinity of thiol-rich small peptides phytochelatins beyond glutathione.Metallomics. 2021, 13, mfab068.

Shimada, N.; Sugimoto, T.; Noguchi, M.; Ohira, C.; Kuwashima, Y.; Takahashi, N.; Sato, N.; Makino, K. Boronic Acid-Catalyzed Regioselective Koenigs-Knorr-Type Glycosylation. J. Org. Chem. 2021, 86, 5973-5982.

Shirahata, T.; Ishikawa, H.; Kudo, T.; Takada, Y.; Hoshino, A.; Taga, Y.; Minakuchi, Y.; Hasegawa, T.; Horiguchi, R. Hirayama, T.; Konishi, T.; Takemoto, H.; Sato, N.; Kodaira, E.; Fukuda, T.; Kobayashi, Y. Metabolic fingerprinting for discrimination of DNA-authenticated Atractylodesplants using ¹H NMR spectroscopy. J. Nat. Med. 2021, 75, 475-488.

Itoh, K.; Nagao, SI.; Tokunaga, K.; Hirayama, S.; Karaki, F.; Mizuguchi, T.; Nagai, K.; Sato, N.; Suzuki, M.; Hashimoto, M.; Fujii, H. Visible-Light-Induced Synthesis of 1,2,3,4-Tetrahydroquinolines through Formal [4+2] Cycloaddition of Acyclic α,β-Unsaturated Amides and Imides with N,N-Dialkylanilines. Chem.Eur.J. 2021, 27, 5171-5179.

2020

Fukuda, T.; Nagai, K.; Kanamoto, A.; Tomoda, H. 2-Epi-anthracimycin, a new cytotoxic agent from the marine-derived actinomycete Streptomyces sp. OPMA00631. J. Antibiot. 2020, 73, 548-533.

Yoshida, K.; Kawamura, C.; Yamazaki, N.; Sato, N.; Nagai, K.; Kaji, E.; Kurasawa, Y. Synthesis of 2-arylhydrazono-4-chloro-3-oxobutanoates existing as (E)/(Z)-hydrazone isomers in solution: correlation between equilibrium constants and substituent constants. J. Mol. Struct. 2020, 1199:126960,1-5.

2019

 Fukuda, T.; Nagai, K.; Yagi, A.; Kobayashi, K.; Uchida, R.; Yasuhara, T.; Tomoda, H. Nectriatide, a Potentiator of Amphotericin B Activity from Nectriaceae sp. BF-0114. J. Nat. Prod. 2019, 82, 2673-2681.

Fukuda, T.; Furukawa, T.; Kobayashi, K.; Nagai, K.; Uchida, R.; Tomoda, H. Helvamide, a new inhibitor of sterol O-acyltransferase produced by the fungus Aspergillus nidulans BF-0142. J. Antibiot. 2019, 72, 8-14.

Itoh, K.; Odate, F.; Karikomi, T.; Obe, K.; Miyamori, T.; Kamiya, H.; Yoza, K.; Nagai, K.; Fujii, H.; Suga, H.; Tokunaga, K. Novel asymmetric photodimerization reaction of coumarin derivatives bearing a chiral 2-oxazolidinone auxiliary. RSC Adv., 2019, 9, 12365-12369.

Karaki, F.; Umemoto, S.; Ashizawa, K.; Oki, T.; Sato, N.; Ogino, T.; Ishibashi, N.; Someya, R.; Miyano, K.; Hirayama, S.; Uezono, Y.; Fujii, H. A New Lead Identification Strategy: Screening an sp³-rich and Lead-like Compound Library Composed of 7-Azanorbornane Derivatives. ChemMedChem 2019, 14, 1840-1848.

2018

Koizumi, Y.; Nagai, K.; Gao, L.; Koyota, S.; Yamaguchi, T.; Natsui, M.; Imai, Y.; Hasumi, K.; Sugiyama, T.; Kuba, K. Involvement of RSK1 activation in malformin-enhanced cellular fibrinolytic activity. Sci. Rep. 2018, 8:5472.

Ohshiro, T.; Seki, R.; Fukuda, T.; Uchida, R.; Tomoda, H. Celludinones, new inhibitors of sterol O-acyltransferase, produced by Talaromycescellulolytius BF-3007. J. Antibiot. 2018, 71, 1000-1007.

Ohtawa, M.; Arima, S.; Ichida, N.; Terayama, T.; Ohno, H.; Yamazaki, T.; Ohshiro, T.; Sato, N.; Omura, S.; Tomoda, H.; Nagamitsu, T. Design and Synthesis of A-Ring Simplified Pyripyropene A Analogues as Potent and Selective Synthetic SOAT2 Inhibitors. ChemMedChem 2018, 13, 411-421.