Laboratory of Microbial Chemistry

Catalindoles A-C, brominated indole alkaloids from a starfish Thromidia catalai feeding on Theonella sponges

Matsuta R, Shigeno S, Ohshiro T, Ueda M, Takada K.
Fish Sci.,  accepted (2024)

https://link.springer.com/article/10.1007/s12562-024-01803-z
 

The new seriniquinone glycoside by biological transformation using the deep sea-derived bacterium Bacillus licheniformis KDM612

Okamura R, Kikuchi K, Taniguchi A, Nagai K, Seki R, Ohte S, Ohshiro T, Ando M, Tanaka T, Fukuda T.
J Antibiot.,  in press (2024)
https://pubmed.ncbi.nlm.nih.gov/38773230/

Paranazzamides A and B, new cyclic dipeptides containing a C7-prenylated tryptophan, produced by pathogenic reptile fungi Paranannizziopsis sp. UH-21.

Kobayashi K, Tejima R, Nagai K, Seki R, Hosoya T, Une Y, Shigeno S, Tomoda H, Ohshiro T.
J Antibiot., 77 :403-411 (2024)
https://pubmed.ncbi.nlm.nih.gov/38750250/

 

New polycyclic tetramate macrolactams with antimycobacterial activity produced by marine-derived Streptomyces sp. KKMA-0239.

Shigeno S, Kadowaki M, Nagai K, Hosoda K, Terahara T, Nishimura T, Hasegawa N, Tomoda H, Ohshiro T.
J Antibiot., 77 :265-271 (2024)
https://pubmed.ncbi.nlm.nih.gov/38531967/

Mavintramycin A is a promising antibiotic for treating Mycobacterium avium complex infectious disease

Hosoda K, Koyama N, Shigeno S, Nishimura T, Hasegawa N, Kanamoto A, Ohshiro T, Tomoda H.
Antimicrob Agents Chemother., 68 :e0091723 (2024)
https://pubmed.ncbi.nlm.nih.gov/38334410/

Synthesis and biological evaluation of nectriatide derivatives, potentiators of amphotericin B activity

Nagai K, Kobayashi K, Miyake R, Sato Y, Seki R, Fukuda T, Yagi A, Uchida R, Ohshiro T, Tomoda H.
J Antibiot., 77 :214-220 (2024)
https://pubmed.ncbi.nlm.nih.gov/38267575/

Total synthesis of tanzawaic acid A.

Tanaka K, Suzuki S, Lee D, Arima S, Ohte S, Ohshiro T, Uchida R, Tomoda H, Nagamitsu T.
Tetrahedron, 143 :133556 (2023)
https://www.sciencedirect.com/science/article/pii/S0040402023003587

Haneummycin, a new 22-membered macrolide lactam antibiotic, produced by marine-derived Streptomyces sp. KM77-8

Uemura M, Kobayashi K, Sato N, Nagai K, Seki R, Kamio M, Fukuda T, Tsubouchi T, Tomoda H, Ohshiro T, Kobayashi T, Terahara T.
J Antibiot., 76 :650-657 (2023)
https://pubmed.ncbi.nlm.nih.gov/37726436/

Astaxanthin Attenuates Nonalcoholic Steatohepatitis with Downregulation of Osteoprotegerin in Ovariectomized Mice Fed Choline-Deficient High-Fat Diet.

Zhao M, Ma L, Honda T, Kato A, Ohshiro T, Yokoyama S, Yamamoto K, Ito T, Imai N, Ishizu Y, Nakamura M, Kawashima H, Tsuji NM, Ishigami M, Fujishiro M.
Dig Dis Sci., 68 :155-168 (2023)
https://pubmed.ncbi.nlm.nih.gov/35397697/

Screening for microbial potentiators of neutral lipid degradation in CHO-K1 cells.

Nur EAA, Kobayashi K, Ohte S, Tomoda H,?Ohshiro T.
Drug Discov Ther.?, 16 :273-279 (2022)
https://pubmed.ncbi.nlm.nih.gov/36450503/