Laboratory of Microbial Chemistry

Raman Imaging of an Amphotericin B Potentiator in Single-Cell Saccharomyces cerevisiae

Miyake R, Ando M, Kobayashi K, Nagai K, Ohshiro T, Tomoda H, Takeyama H..
J Phys Chem B., 129 :5720-5727 (2025)
https://pubmed.ncbi.nlm.nih.gov/40446163/

Nectriatides with no antifungal activity bind to ergosterol and potentiate the antifungal activity of amphotericin B against Candida albicans

Kobayashi K, Miyake R, Nagai K, Sato Y, Seki R, Sakai-Kato K, Nishimura S, Ohshiro T, Tomoda H..
BioRxiv,  : (2025)
https://www.biorxiv.org/content/10.1101/2025.02.04.636370v1

Streptomyces haneummycinicus sp. nov., a new antibiotic-producing actinomycete isolated from marine sediment

Uemura M, Hamada M, Hirano S, Kobayashi K, Ohshiro T, Tsubouchi T, Kobayashi T, Terahara T..
Int J Syst Evol Microbiol., 75 :accepted (2025)
https://pubmed.ncbi.nlm.nih.gov/40354190/

Catalytic Enantioconvergent Alkylation Reactions That Construct Chiral Quaternary Carbon Centers and Tune C(sp3)-C(sp2) Bond Rotation

Sohail M, Kobayashi K, Tomoda H, Ohshiro T, Tanaka F..
Chemistry, 31 :e202500140 (2025)
https://pubmed.ncbi.nlm.nih.gov/39960741/

Evaluation of tirandamycins with selective activity against Enterococci in the silkworm infection model

Yagi A, Sato T, Kano C, Igari T, Oshima N, Ohte S, Ohshiro T, Uchida R.
J Antibiot., 78 :211-218 (2025)
https://pubmed.ncbi.nlm.nih.gov/39953284/

Celludinone C, a new dihydroisobenzofuran isolated from Talaromyces cellulolyticus BF-0307.

Seki R, Nagai K, Kobayashi K, Shigeno S, Shirahata T, Kobayashi Y, Ohshiro T, Tomoda H.
J Antibiot., 78 :26-34 (2025)
https://pubmed.ncbi.nlm.nih.gov/39543335/

Total syntheses of mavintramycin A and its structural analog, cytosaminomycin C, and evaluation of their antibacterial activities against Mycobacterium avium and Mycobacterium intracellulare.

Satoh H, Lee D, Arima S, Hosoda K, Shigeno S, Tomoda H, Ohshiro T, Nagamitsu T.
Tetrahedron, 168 :134299 (2024)
https://www.sciencedirect.com/science/article/abs/pii/S0040402024004800

Drimane sesquiterpene esters produced by Aspergillus insuetus BF-1613 as inhibitors of sterol O-acyltransferase.

Nur EAA, Kobayashi K, Tejima R, Katada Y, Tomoda H, Ohshiro T.
J Antibiot., 77 :837-841 (2024)
https://pubmed.ncbi.nlm.nih.gov/39385005/

Catalindoles A-C, brominated indole alkaloids from a starfish Thromidia catalai feeding on Theonella sponges

Matsuta R, Shigeno S, Ohshiro T, Ueda M, Takada K.
Fish Sci., 90 :787-793 (2024)
https://link.springer.com/article/10.1007/s12562-024-01803-z

The new seriniquinone glycoside by biological transformation using the deep sea-derived bacterium Bacillus licheniformis KDM612

Okamura R, Kikuchi K, Taniguchi A, Nagai K, Seki R, Ohte S, Ohshiro T, Ando M, Tanaka T, Fukuda T.
J Antibiot., 77 :515-521 (2024)
https://pubmed.ncbi.nlm.nih.gov/38773230/