Laboratory of Molecular Pharmacology
Laboratory of Molecular Pharmacology
Japanese
Research Achievements
Kashihara T, Morita Y, Hatta M, Inoue S, Suzuki Y, Morita A, Nakahara T.
YAP activation in Müller cells protects against NMDA-induced retinal ganglion cell injury by regulating Bcl-xL expression.
Front Pharmacol. 2024 Aug 6;15:1446521
Nakamura R, Iwai T, Takanezawa Y, Shirahata T, Konishi N, Ohshiro Y, Uraguchi S, Tanabe M, Kobayashi Y, Sakamoto K, Nakahara T, Yamamoto M, Kiyono M.
Oleanolic acid-3-glucoside, a synthetic oleanane-type saponin, ameliorates methylmercury-induced dysfunction of synaptic transmission in mice. Toxicology. 2024 Aug;506:153867.
doi: 10.1016/j.tox.2024.153867.Tomita M, Matsumoto T, Morita A, Itokawa T, Nakahara T, Hori Y.
Optic Nerve Blood Flow in Neonatal Rats with Retinopathy of Prematurity-Like Abnormal Vascular Growth Induced by Vascular Endothelial Growth Factor Receptor Inhibitors
Toho Journal of Medicine. 2024.03;10(1):18-27.
Yamagishi H, Kirai N, Morita A, Kashihara T, Nakahara T.
Role of monocarboxylate transporters in AMPK-mediated protection against excitotoxic injury in the rat retina.
Eur J Pharmacol. 2024 May 5;970:176510.
Sone K, Mori A, Sakamoto K, Nakahara T.
The Role of microRNAs Related to Apoptosis for N-Methyl-d-Aspartic Acid-Induced Neuronal Cell Death in the Murine Retina.
Int J Mol Sci. 2024 Jan 16;25(2):1106.
Yagasaki R, Morita A, Mori A, Sakamoto K, Nakahara T.
The Anti-Diabetic Drug Metformin Suppresses Pathological Retinal Angiogenesis via Blocking the mTORC1 Signaling Pathway in Mice (Metformin Suppresses Pathological Angiogenesis).
Curr Eye Res. 2024 May;49(5):505-512
Nakano A, Morita A, Arima S, Nagamitsu T, Nakahara T.
Role of mammalian target of rapamycin in the formation and progression of retinopathy of prematurity-like vascular abnormalities in neonatal rats.
Microvasc Res. 2024 Mar;152:104626.
Kamiya E, Morita A, Mori A, Sakamoto K, Nakahara T.
The process of methylglyoxal-induced retinal capillary endothelial cell degeneration in rats.
Microvasc Res. 2023 Mar;146:104455.
Mori A, Ezawa Y, Asano D, Kanamori T, Morita A, Kashihara T, Sakamoto K, Nakahara T.
Resveratrol dilates arterioles and protects against N-methyl-d-aspartic acid-induced excitotoxicity in the rat retina.
Neurosci Lett. 2023 Jan 10;793:136999.
Asano D, Kojima M, Morita A, Nakahara T.
Tumor necrosis factor-α and matrix metalloproteinase-9 cooperatively exacerbate neurovascular degeneration in the neonatal rat retina.
Cell Tissue Res. 2022 Nov;390(2):173-187.