Laboratory of Clinical Pharmacoepidemiology
Laboratory of Clinical Pharmacoepidemiology
Japanese
The field of pharmacoepidemiology is a field of research that has developed in response to the needs of society and is connected to clinical pharmacology and epidemiology.
Pharmacoepidemiology (pharmacoepidemiology) is a field of study and research that has continued to develop in response to the demands of society and is also called the "bridge science" that connects clinical pharmacology and epidemiology.
In this laboratory, we will face the issues and questions of pharmacotherapy in the medical field and research how to improve pharmacotherapy, focusing on pharmacoepidemiological research that utilizes medical information.
Research Achievements
Hepatic Adaptation to Therapeutic Doses of Acetaminophen: An Exploratory Study in Healthy Individuals.
Mika Maeda;Rieko Tanaka;Masako Aso;Yasutoshi Sakamoto;Ildae Song;Michiru Ochiai;Yoshiro Saito;Keiko Maekawa;Noriaki Arakawa;Yasuo Ohno;Yuji Kumagai.
Clinical therapeutics, 42 (7) :1276-1291 (2020)
A Drug-Drug Interaction Study to Evaluate the Effect of TAS-303 on CYP3A Activity in the Small Intestine and Liver.
Yuji Kumagai;Tomoe Fujita;Mika Maeda;Yoshinobu Sasaki;Makoto Nagaoka;Jinhong Huang;Toru Takenaka;Masaki Kawai.
Journal of clinical pharmacology, 60 (6) :702-710 (2020)
A 3-Part Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DSP-6952 in Healthy Japanese Subjects and Those With ≤3 Spontaneous Bowel Movements per Week.
Takuya Yumizaki;Mika Maeda;Tomoe Fujita;Hiroyoshi Kakuyama;Yuji Kumagai.
Clinical pharmacology in drug development, 9 (3) :353-365 (2020)
Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial.
Yuji Kumagai; Hideki Amano; Yoshinobu Sasaki; Chie Nakagawa; Mika Maeda; Ichiro Oikawa; Hidetoshi Furuie.
British journal of clinical pharmacology, 84 (10) :2393-2404 (2018)
Pharmacokinetics and Pharmacodynamics of a Single Dose of Scopolamine Ointment Applied to the Postauricular Area in Healthy Subjects
Maeda Mika; Fujita Tomoe; Amano Hideki; Kohara Harue; Yamazaki Akira; Hirayama Takeshi; Kuroyama Masakazu; Ogino Mieko; Nagashima Kazuaki; Akutsu Tsugio; Nishiyama Kazutoshi; Kumagai Yuji.
Japanese Journal of Clinical Pharmacology and Therapeutics, 49 (2) :53-58 (2018)
Influences of Long-Term, High-Dose Acetaminophen Administration on Liver Function Markers in Healthy Japanese Adults
Song Ildae; Tanaka Rieko; Aso Masako; Sakamoto Yasutoshi; Maeda Mika; Ochiai Michiru; Saito Yoshiro; Maekawa Keiko; Kumagai Yuji.
Japanese Journal of Clinical Pharmacology and Therapeutics, 48 (5) :153-159 (2017)
Population Pharmacokinetic-Pharmacodynamic Analysis to Compare the Effect of Moxifloxacin on QT Interval Prolongation Between Healthy Korean and Japanese Subjects.
Population Pharmacokinetic-Pharmacodynamic Analysis to Compare the Effect of Moxifloxacin on QT Interval Prolongation Between Healthy Korean and Japanese Subjects..
Clinical therapeutics, 38 (12) :2610-2621 (2016)
Comparative Pharmacokinetic Study of Acetaminophen in Japanese and Han Chinese Individuals
Hyang-Ki Choi; Jin Ah Jung; Tomoe Fujita; Hideki Amano; Jong-Lyul Ghim; Dong-Hwan Lee; Kenichi Tabata; Il-Dae Song; Mika Maeda; Yuji Kumagai; Boaz Mendzelevski; Jae-Gook Shin.
Japanese Journal of Clinical Pharmacology and Therapeutics, 47 (1) :11-16 (2016)